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The ripoptosome phosphorylates mixed-lineage kinase domain-like protein (MLKL), and the phosphorylated MLKL activates mitochondrial ROS production

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As a positive control for a scavenging reaction involving glutathione, we repeated our time-kill experiments with treatment by exogenous peroxynitrite 38 with and without pretreatment by glutathione (10 mM)